A recently published report shows that high intake of the dietary omega-6 arachidonic acid could increase your risk for colorectal adenoma. Omega-6 arachidonic acid is associated with a higher risk for colorectal cancer, whereas omega-3s protect against the disease. A total of 681 individuals aged 40-75 years old with tubular adenomas, 223 with advanced adenomas and 835 polyp-free controls were analyzed.
Adenoma risk increased with increasing amounts of arachidonic acid in the RBC membrane; the risk was even higher for advanced adenomas. By contrast, individuals with the highest membrane levels of the omega-3 DHA were at a significantly lower risk for adenoma compared to individuals who had the lowest levels. A reduction in the risk for advanced adenoma was seen with increasing levels of the omega-3 EPA.