Supplements of the omega 3 DHA were shown to stop the progression of nonalcoholic steatohepatitis, or NASH, into more serious and life-threatening health problems such as cirrhosis or liver cancer. This took place even with the continued consumption in lab animals of what scientists call a “western” diet – one that’s high in fat, sugar and cholesterol. NASH, which is characterized by liver inflammation, oxidative stress and fibrosis, is a substantial risk factor for cirrhosis and liver cancer. It’s predicted to be the leading cause of liver transplants by 2020, and the FDA currently has no approved medical treatments for it.
Based in large part on consuming the “western diet,” nearly 80 million adults and 13 million children in the United States are obese, and about 30 percent of the nation’s population is estimated to have some form of chronic fatty liver disease. Research has also shown that when humans with NASH are examined, they have very low levels of omega 3 fatty acids. When those levels are raised, the disease progression stops. Omega 3 fatty acids regulate important biological pathways, including fatty acid synthesis, oxidation, and breakdown of triglycerides, or fats in the blood. A natural nutrient, DHA appears to be one of the most significant of the omega 3 fatty acids, and plays a role in repairing liver damage.