A Danish study of patients with inflammatory bowel disease (IBD) and Parkinson disease (PD) found that patients with IBD had a 22% increased risk of developing PD over patients without IBD. The study, published in Gut, examined all Danish residents aged 15 years or older from 1977 to 2014 in the largest and longest population-based study of links between enteric inflammation and PD.
The possibility that PD may originate in the gut is also supported by discoveries of close associations between PD and inflammatory markers, including tumor necrosis factor-alpha and interleukin 6, which are present in patients with ulcerative colitis, IBD, and Crohn disease.
Read more at: https://www.neurologyadvisor.com/topics/movement-disorders/gut-inflammation-linked-to-the-development-of-parkinson-disease/