Schizophrenia is a complex psychiatric disorder involving a wide range of cognitive, emotional, and social function impairments and altered brain structure. Recent findings suggest a continuum approach: that continuous symptoms and psychiatric disorder related traits can be integrated as risk features for the development of the corresponding disorders.
In order to bridge this gap of knowledge, Dr. Raymond Chan and his team members from the Institute of Psychology of the Chinese Academy of Sciences (CAS) have examined the brain structural and functional connectivity changes associated with schizotypy.
People with schizotypal traits exhibited increased structural connectivity probability within the task control network and default mode network. They also had increased variability and decreased stability of functional connectivity within the DMN and between the auditory and subcortical networks.