Restarting warfarin (Coumadin) after a traumatic brain injury (TBI) improved overall outcomes despite the bleeding risk, an observational Medicare study showed.
The strategy was associated with lower risk of hemorrhagic and ischemic stroke together, with a net reduction in relative risk to 0.83 compared with no warfarin after discharge for TBI (95% CI 0.72-0.96), the researchers reported in the August issue of JAMA Internal Medicine.