study identifying additional therapeutic opportunities of cannabidiol (CBD), which include the potential to prevent post-traumatic stress disorder (PTSD). Researchers found that CBD can significantly reduce the conditioned fear expression and fear generalization and the relative resistance to extinction of the fear memory. Their research suggests the mechanism of action is through CBD’s known effects on increasing

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Impairment of amyloid-β (Aβ) clearance leads to Aβ accumulation in the brain during the development of Alzheimer’s disease (AD). Strategies that can restore or improve the clearance function hold great promise in delaying or preventing the onset of AD. Here, we show that n-3 polyunsaturated fatty acids (PUFAs), by use of fat-1 transgenic mice and

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The cannabinoid receptor-2 (CB2R) was initially thought to be the “peripheral cannabinoid receptor.” Recent studies, however, have documented CB2R expression in the brain in both glial and neuronal cells, and increasing evidence suggests an important role for CB2R in the central nervous system inflammatory response. Stimulation of CB2R using a selective agonist ameliorated brain edema, brain

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Using a form of low-impulse electrical stimulation to the brain, documented by neuroimaging, researchers report significantly improved neural function in participants with mild TBI. Their findings are published online in the current issue of the journal Brain Injury. In their pilot study, which involved six participants who had suffered mild TBI and experienced persistent post-concussion symptoms, the researchers

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Recovering from a concussion typically takes female athletes more than twice as long as males, according to a new study that tracked hundreds of teenagers active in sports. The finding adds to a growing body of evidence that vulnerability to this injury—and aspects of the healing process—may vary by sex. Their analysis revealed the median recovery

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In a study published in the September 26 issue of JAMA, investigators analyzed data on 13,088 adolescents aged 12 to 18 years and found that an estimated 19.5% of students reported at least one diagnosed concussion, with 14.0% reporting one concussion and 5.5% reporting more than one concussions. About 22% of adolescents reporting a diagnosed concussion played a contact sport,

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Minerals are critical in supporting several key functions related to mood disorders, including neuro­ transmitter synthesis, cellular metabolism, and immunocompetence. Modern-day malnutrition has been attributed to poor dietary patterns, marked by excess intake of refined sugars and the absence of nutrient-dense foods. In a population study that included 13,486 children and adolescents, excess consumption of low

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A new study suggests that almost all adults in Western countries still fall far below optimal blood levels of these important nutrients. The study, published in a recent issue of Nutrients, found that 98% of participants from the US and Germany, fell below the optimum 8.0 Omega-3 Index Level. More than half of the participants in

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Biomarkers offer the potential to supplement traditional diagnosis and classification of TBI.  In a recent study published in JAMA Neurology, a research team from the US, Egypt, and Kuwait investigated the efficacy of three plasma biomarkers to accurately distinguish acute mild and chronic TBI: hypophosphorylated tau protein (P-tau); total tau (T-tau) protein; and the ratio of P-tau to

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